Bio:

I obtained my bachelor and master degrees of medicine in Harbin Medical University and moved to University of Ottawa in 2017. I am currently working with Dr. Laurie Chan using hESCs to look at the developmental toxicity of methylmercury and chemical mixtures.

Research Project:

Evaluating and comparing the effects of methylmercury and northern contaminant mixture on human embryonic stem cells.
Understanding the effects of methylmercury on endodermal development.

Publications:

Florian, M., Li, B., Patry, D., Truong, J., Caldwell, D., Coughlan, M.C., Woodworth, R., Yan, J., Chen, Q., Petrov, I. and Mahemuti, L., 2022. Interplay of Obesity, Ethanol, and Contaminant Mixture on Clinical Profiles of Cardiovascular and Metabolic Diseases: Evidence from an Animal Study. Cardiovascular Toxicology, 22(6), pp.558-578. https://europepmc.org/article/med/35429258

Li, B., Qiao, C., Jin, X. and Chan, H.M., 2021. Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells. Environmental health perspectives, 129(7), p.077007. https://doi.org/10.1289/EHP7349

Liu, F., Yuan, M., Li, C., Guan, X. and Li, B., 2021. The protective function of taurine on pesticide‐induced permanent neurodevelopmental toxicity in juvenile rats. The FASEB Journal, 35(1), p.e21273. https://doi.org/10.1096/fj.202001290R

Wang, D., Li, B., Wu, Y. and Li, B., 2019. The effects of maternal atrazine exposure and swimming training on spatial learning memory and hippocampal morphology in offspring male rats via PSD95/NR2B signaling pathway. Cellular and molecular neurobiology, 39(7), pp.1003-1015. https://pubmed.ncbi.nlm.nih.gov/31187311/ Jiang, W., Li, B., Chen, Y. and Gao, S., 2017. The toxic influence of dibromoacetic acid on the hippocampus and pre-frontal cortex of rat: involvement of neuroinflammation response and oxidative stress. Metabolic Brain Disease, 32(6), pp.2009-2019. https://pubmed.ncbi.nlm.nih.gov/28844098/

Jiang, W., Chen, Y., Li, B. and Gao, S., 2017. DBA-induced caspase-3-dependent apoptosis occurs through mitochondrial translocation of cyt-c in the rat hippocampus. Molecular BioSystems, 13(9), pp.1863-1873. https://doi.org/10.1039/C7MB00246G

Sun, Y., Li, Y.S., Li, B., Ma, K. and Li, B.X., 2017. A study of the age-related effects of lactational atrazine exposure. Reproductive toxicology, 69, pp.230-241. https://doi.org/10.1016/j.reprotox.2017.03.011

Li, B., He, X., Sun, Y. and Li, B., 2016. Developmental exposure to paraquat and maneb can impair cognition, learning and memory in Sprague-Dawley rats. Molecular BioSystems, 12(10), pp.3088-3097. https://doi.org/10.1039/C6MB00284F

Conferences:

Li, B., Jin, X., & Chan, H. M., Effects of low doses of methylmercury (MeHg) on definitive endoderm differentiation during early embryo development. Joint SDB-PASEDB Meeting. Poster presentation. Vancouver, Canada, Jul 2022.

Li, B., Pan, Y., Jin, X., & Chan, H. M., Investigation of the effects of a contaminant mixture on early-stage embryo development using cultured human embryonic stem cells. Joint SDB-PASEDB Meeting. Poster presentation. Vancouver, Canada, Jul 2022.

Florian, M., Li, B., Patry, T., et al., Interplay of Obesity, Ethanol, and a Contaminant Mixture on Physiological and Clinical Markers of Cardiovascular and Metabolic Diseases: Evidence from an Animal. Health Canada Science Forum. Poster presentation. Online, Feb 2022.

Li, B., Jin, X., & Chan, H. M., Effects of low doses of methylmercury on cultured human embryonic stem cells. Health Canada Science Forum. Oral presentation. Ottawa, Canada, Jan 2020.

Li, B., Jin, X., & Chan, H. M., Effects of low doses of methylmercury on cultured human embryonic stem cells. 51st STC Symposium. Poster presentation. Ottawa, Canada, Dec 2019.

Li, B., Jin, X., & Chan, H. M., Characterizing the low dose effects of methylmercury in early developmental stages using cultured human embryonic stem cells. 55th Congress of the European Societies of Toxicology. Poster presentation. Helsinki, Finland, Sep 2019.